Chlamydial conjunctivitis (ocular Chlamydia infection)
Conditions
Interventions
None listed
Sponsors
Yokohama City University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Original articles evaluating the diagnostic accuracy (sensitivity and specificity) of nucleic acid amplification tests (NAATs) for ocular infections caused by Chlamydia trachomatis, including case-control, cross-sectional, prospective, and retrospective studies. Eligible studies must use conjunctival swabs or ocular discharges as specimens, and reference standards such as clinical diagnosis by physicians, culture methods, or DFA. Literature search will be conducted using PubMed and Web of Science, supplemented by manual reference and guideline review.
Exclusion criteria
Exclusion criteria: Studies reporting only sensitivity or specificity, which are insufficient for bivariate meta-analysis, will be excluded. In addition, duplicate studies judged to be based on the same dataset will be carefully reviewed and excluded if necessary.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of NAATs for the diagnosis of chlamydial ocular infections | — |
Secondary
| Measure | Time frame |
|---|---|
| Area under the SROC curve (AUC), diagnostic odds ratio (DOR), and heterogeneity (I^2) | — |
Countries
Japan
Contacts
Public ContactYuki Mizuki
Yokohama City University Hospital Department of Ophthalmology
Outcome results
None listed