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A Study on the Impact of Intraoperative Blood Pressure and Circulating Plasma Volume on Renal Perfusion

A Study on the Impact of Intraoperative Blood Pressure and Circulating Plasma Volume on Renal Perfusion - A Study on the Impact of Intraoperative Blood Pressure and Circulating Plasma Volume on Renal Perfusion

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000057845
Enrollment
30
Registered
2025-05-13
Start date
2025-04-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients scheduled for surgery under general anesthesia

Interventions

Before induction of anesthesia in the operating room, ultrasound is used to identify the location of the left and right kidneys, and NIRS sensors are then applied to the corresponding areas on the bac
standard anesthetic management will be maintained, and NIRS values will be continuously monitored. The fraction of inspired oxygen (FiO2) will be maintained at 60% throughout the surgery.

Sponsors

Jichi medical university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged 65 years or older Patients diagnosed with hypertension and receiving antihypertensive medication Patients scheduled for elective surgery requiring both arterial catheter insertion and cardiac output monitoring Patients scheduled for surgery in the supine position Patients in whom preoperative CT imaging shows a distance of less than 30 mm from the skin surface of the back to the surface of either kidney In the absence of preoperative trunk CT, patients with a body mass index (BMI) of less than 18

Exclusion criteria

Exclusion criteria: Patients with an ejection fraction <40% Patients with atrial fibrillation Patients with severe chronic obstructive pulmonary disease (COPD) Patients with right heart failure Patients undergoing surgery requiring one-lung ventilation Patients with chronic kidney disease (eGFR <60 mL/min/1.73 m2) Patients requiring cardiopulmonary bypass Patients undergoing aortic surgery Patients undergoing surgery involving the kidneys or adrenal glands Patients with documented carotid artery stenosis Patients in whom preoperative ultrasound on the day of surgery shows a distance of >30 mm from the skin surface to the kidney surface

Design outcomes

Primary

MeasureTime frame
Renal tissue oxygenation measured by NIRS during surgery

Secondary

MeasureTime frame
cerebral tissue oxygenation measured by NIRS

Countries

Japan

Contacts

Public ContactYUSUKE IIZUKA

Jichi medical university, saitama medical center Department of anesthesiology and critical care medicine

zukarinn@gmail.com+81486472111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026