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Evaluation of the Diagnostic Utility of the MBDA Score and Related Biomarkers for Early Detection of Rheumatoid Arthritis in Patients with Undifferentiated Arthritis: A Comparison of AORA and EORA

Evaluation of the Diagnostic Utility of the MBDA Score and Related Biomarkers for Early Detection of Rheumatoid Arthritis in Patients with Undifferentiated Arthritis: A Comparison of AORA and EORA - MBDA and Biomarkers in Early RA Diagnosis (AORA/EORA)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000057829
Enrollment
167
Registered
2025-05-11
Start date
2019-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthritis, Undifferentiated arthritis

Interventions

None listed

Sponsors

Hokkaido University of Science
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with undifferentiated arthritis who presented with joint pain within 6 months of onset and visited a medical facility Patients from whom residual serum samples obtained for clinical purposes at first visit were available and used for this study with written informed consent Patients for whom ACPA, RF, and MBDA score could be measured

Exclusion criteria

Exclusion criteria: Patients from whom serum samples were not collected or not stored at the initial visit Patients whose residual serum was insufficient for measuring ACPA, RF, or MBDA score Patients who had received any treatment for rheumatoid arthritis (e.g., DMARDs, biologics, JAK inhibitors) or corticosteroids prior to or at the initial visit Patients who did not provide written informed consent

Design outcomes

Primary

MeasureTime frame
Accuracy of baseline MBDA score in predicting RA diagnosis at 3-year follow-up

Countries

Japan

Contacts

Public ContactKazuay Hiura

Hokkaido University of Science Faculty of Pharmaceutical Sciences

hiura-k@hus.ac.jp0116768574

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026