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The Efficiency of Cryo or Compression Therapy in the Prevention of Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Network Meta-Analysis

The Efficiency of Cryo or Compression Therapy in the Prevention of Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Network Meta-Analysis - NMA-CIPN

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000057786
Enrollment
200
Registered
2025-05-07
Start date
2025-04-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chemotherapy-Induced Peripheral Neuropathy

Interventions

None listed

Sponsors

Teikyo University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The inclusion criteria comprised RCTs that met the following conditions:1 evaluated the preventive effects of cryotherapy, compression therapy, or cryocompression therapy on CIPN; 2 enrolled adult patients (aged >=8 years) receiving neurotoxic chemotherapy; 3 assessed CIPN occurrence as an outcome of the intervention; and 4 included self-controlled designs, which were considered acceptable.

Exclusion criteria

Exclusion criteria: Studies were excluded if they met any of the following criteria: (1) the intervention was not intended for prevention; (2) the study was not a randomized controlled trial; or (3) the data were not comparable.

Design outcomes

Primary

MeasureTime frame
The primary outcome was the incidence of CIPN.—

Secondary

MeasureTime frame
Safety—

Countries

Japan,Asia(except Japan),North America,South America,Australia,Europe,Africa

Contacts

Public ContactHao Chen

Teikyo University Hospital Department of chemotherapy

chinsmd@gmail.com03-3964-1211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026