Study on the usefulness of preceding fever or shaking chills in identifying septic arthritis among patients with acute monoarthritis

Retrospective diagnostic accuracy study on the clinical utility of preceding fever or shaking chills for diagnosing septic arthritis in acute monoarthritis - PREF-SA study (PReceding Fever for Septic Arthritis study)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057767

Enrollment

224

Registered

2025-05-06

Start date

2025-04-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

septic arthritis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patient inclusion criteria were all of the following: (a) age of 18 years or older; (b) no penetrating joint injury; (c) no history of affected joint surgery within one year; (d) no prosthetic implantation of the affected joint; and (e) joint aspiration was performed and synovial fluid was submitted for analysis in the emergency department.

Exclusion criteria

Exclusion criteria: Patients were excluded if they met any of the following criteria: (a) joint aspiration was performed but no synovial fluid was obtained and submitted for analysis (i.e., dry tap); (b) diagnosis of bursitis instead of arthritis; (c) diagnosis of tuberculous arthritis.

Design outcomes

Primary

Measure	Time frame
Diagnostic performance (sensitivity, specificity, and likelihood ratios) of preceding fever or shaking chills for identifying septic arthritis in patients with acute monoarthritis	—

Countries

Japan

Contacts

Public ContactYasuhiro Kano

Tokyo Metropolitan Tama Medical Center Department of Emergency and General Medicine

yasuhiro.kano.21@gmail.com042-323-5111

Outcome results