Patients undergoing thoracic surgery
Conditions
Interventions
Individualized blood pressure management targeting within 15% of preoperative baseline mean arterial pressure.
Standard blood pressure management targeting a mean arterial pressure >
60 mmHg intraoperatively.
Sponsors
Osaka Metropolitan University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients undergoing thoracic surgery requiring one-lung ventilation under general anesthesia. 2.Patients undergoing invasive arterial blood pressure monitoring.
Exclusion criteria
Exclusion criteria: 1.Patients undergoing emergency surgery. 2.Patients whose baseline mean arterial pressure is below 70 mmHg. 3.Patients with impaired renal function (preoperative estimated glomerular filtration rate [eGFR] < 30 mL/min/1.73 m2). 4.Patients requiring controlled hypotension, such as those with concomitant aortic aneurysm. 5.Patients judged inappropriate by the attending anesthesiologist for any other reason. 6.Patients judged inappropriate by the attending thoracic surgeon for any other reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative acute kidney injury | — |
Countries
Japan
Contacts
Public ContactTakashi Juri
Osaka Metropolitan University Graduate School of Medicine Department of Anesthesiology
Outcome results
None listed