Patients aged 18 years or older who are admitted to acute care hospitals (defined as hospitals with ICU, HCU, or equivalent wards [such as those receiving emergency medical care management fees])
Conditions
Interventions
1.5% olanexidine gluconate solution (Olanedine):Olanedine solution 1.5% antiseptic applicator 10ml (Otsuka Pharmaceutical Factory, Inc.) + chlorhexidine-containing dressing (CHG dressing)*3M Tegaderm
Sponsors
Jichi Medical University Saitama Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Peripherally Inserted Central Catheter inserted in patients aged 18 years or older who are admitted to acute care hospitals (defined as hospitals with ICU, HCU, or equivalent wards [such as those receiving emergency medical care management fees])
Exclusion criteria
Exclusion criteria: 1. Patients with allergies to antiseptics 2. Cases where consent could not be obtained from the subject or their close relatives 3. Patients with systemic skin diseases 4. Cases with skin ulcers at the wound site 5. Patients using antimicrobial catheters 6. Patients participating in intervention trials related to CRBSI prevention (e.g., dressing formulations, skin antiseptics, antimicrobial catheters, antimicrobial administration, etc.) 7. Cases deemed difficult to obtain consent, such as in emergencies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of catheter-related infections | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Occurrence of catheter-related infections (rate per 1000 catheter-days) 2. CRBSI (Catheter-Related Bloodstream Infection) 3. In-hospital mortality rate 4. ICU/HCU mortality rate 5. Resistant bacteria (MRSA, Pseudomonas aeruginosa, VRE) incidence rate 6. Adverse events (redness, urticaria, anaphylaxis, contact dermatitis, others) | — |
Countries
Japan
Contacts
Public ContactHideto Yasuda
Jichi Medical University Saitama Medical Center Department of Emergency and Critical Care Medicine
Outcome results
None listed