Chronic pain
Conditions
Interventions
active taVNS
sham stimulation
Sponsors
Hiroshima University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1 Outpatients at Hiroshima University Hospital 2 Aged 18 years or older 3 Experiencing significant interference with daily life due to pain within the past 6 months 4 Meeting the diagnostic criteria for chronic pain (experiencing pain on more than 90 days over the past 6 months) 5 Reporting pain intensity of 30 or higher on a Numerical Rating Scale (NRS 0_100) on more than 45 days during the past 3 months 6 Providing written informed consent
Exclusion criteria
Exclusion criteria: (1) Individuals aged 70 years or older (2) Individuals with mental conditions that make it difficult to understand the purpose of the study (e.g., those with active symptoms of dementia, delirium, hallucinations, delusions, manic episodes, or suicidal ideation; other psychiatric disorders with less severe symptoms are not necessarily excluded) (3) Individuals with severe physical illnesses that prevent participation in the study (4) Individuals with organic brain disorders (e.g., cerebral hemorrhage or cerebral infarction) (5) Individuals with alcohol use disorder or substance use disorder (6) Individuals deemed inappropriate for participation in the study by the principal investigator or co-investigators (7) Individuals who have previously received Cognitive Behavioral Therapy (CBT)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Numeric Rating Scale (NRS) scores before and after CBT | — |
Countries
Japan
Contacts
Public ContactAtsuo Yoshino
Hiroshima University Health Service Center/ Center for Brain Mind and Kansei Science Research
Outcome results
None listed