patients with peripheral facial palsy
Conditions
Interventions
None listed
Sponsors
Saitama Medical University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with peripheral facial palsy who received acupuncture treatment at the Department of Oriental Medicine, Saitama Medical University Hospital between June 1, 2016, and December 31, 2023. ??(Acupuncture treatments included electroacupuncture near the affected facial nerve and needling of the facial muscles.) 2.Patients within two weeks of onset. 3.Patients who underwent ENoG using the modified NLF method. 4.Patients whose FMCR results were recorded in the electronic medical record. 5.Patients whose Yanagihara scores within two weeks of onset were recorded in the electronic medical record.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of either central or peripheral facial nerve palsy. 2.Patients with unknown onset date, medical history, or medication history. 3.Patients without a confirmed diagnosis of the cause of peripheral facial palsy (e.g., insufficient differential diagnosis to conclude Bell's palsy). 4.Patients with ENoG values equal to or greater than 100%. 5.Patients who underwent ENoG more than two weeks after onset. 6.Patients who expressed a desire to be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Two predictive models will be constructed in this study. Model 1 will classify patients into groups based solely on the facial muscle contraction response (FMCR), whereas Model 2 will classify patients into groups based on both the FMCR and the Yanagihara score. Within each model, hazard ratios for achieving the predefined recovery criteria will be estimated for each group. In addition, time-dependent area under the curve (AUC) values at 30, 90, 180, and 360 days after onset will be calculated and compared between the two models using the modified DeLong test, with Holm's procedure applied to adjust for multiple comparisons. | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in electroneurography (ENoG) values between Model 1 and Model 2 will also be examined. In addition, hazard ratios for achieving the predefined recovery criteria will be estimated for comparisons among groups within each model: Model 1, Model 2, and Model 3 will classify patients into groups based on both electroneurography (ENoG) values and the Yanagihara score. Model 4 will classify patients into groups based on the Yanagihara score. Model 5 will classify patients into groups based on ENoG values alone. Hazard ratios for achieving the predefined recovery criteria will be estimated for comparisons among groups within each model. In addition, time-dependent AUC values at 30, 90, 180, and 360 days after onset will be calculated and compared using the modified DeLong test, with Holm's procedure applied to adjust for multiple comparisons | — |
Countries
Japan
Contacts
Public ContactGo Horibe
Saitama Medical University Hospital Department of Oriental Medicine
Outcome results
None listed