Is sleep state related to arterial stiffness following a postprandial rise in blood glucose level?

Is sleep state related to arterial stiffness following a postprandial rise in blood glucose level? - Is sleep state related to arterial stiffness following a postprandial rise in blood glucose level?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057655

Enrollment

165

Registered

2025-04-19

Start date

2023-12-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arteriosclerosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Schedule can be adjusted 2) Body mass index (BMI) is less than 18.5 to 25 kg / m2 3) You can follow the precautions when participating in the experiment 4) No smoking habits 5) Subjects who agree to participate in this study with a written informed consent after receiving sufficient explanation relating to this study.

Exclusion criteria

Exclusion criteria: 1) If you have a chronic disease 2) When the subject has severe physical symptoms and it is difficult to cooperate with the research 3) In addition, if the person in charge of the survey judges it inappropriate to participate

Design outcomes

Primary

Measure	Time frame
Day 1 of Measurement The study is explained to the participant, and written consent is obtained. To assess autonomic nervous function, a wearable heart rate sensor and electrodes are attached to the chest (female examiner for female participants). For physical activity and sleep monitoring, a wrist-worn accelerometer is attached. Participants follow their usual daily routine but are asked to avoid intense exercise, alcohol, and food or drink (except water) after 9:00 PM. Devices should be removed only during bathing and reattached immediately. All measurements are automatic, and the examiner will respond to any issues. Day 2 of Measurement The next morning, participants return in a fasted state. Height, weight, body fat percentage, and BMI are measured. A 75g oral glucose tolerance test (OGTT) is performed, and vascular stiffness, blood pressure, heart rate, blood glucose, and autonomic function are assessed at baseline, 60, and 120 minutes post-ingestion. Questionnaires on sleep, physical activity, and dietary habits are also completed. Total time is approximately 2.5 to 3 hours. All procedures follow relevant professional guidelines.	—

Measure

Time frame

Day 1 of Measurement The study is explained to the participant, and written consent is obtained. To assess autonomic nervous function, a wearable heart rate sensor and electrodes are attached to the chest (female examiner for female participants). For physical activity and sleep monitoring, a wrist-worn accelerometer is attached. Participants follow their usual daily routine but are asked to avoid intense exercise, alcohol, and food or drink (except water) after 9:00 PM. Devices should be removed only during bathing and reattached immediately. All measurements are automatic, and the examiner will respond to any issues. Day 2 of Measurement The next morning, participants return in a fasted state. Height, weight, body fat percentage, and BMI are measured. A 75g oral glucose tolerance test (OGTT) is performed, and vascular stiffness, blood pressure, heart rate, blood glucose, and autonomic function are assessed at baseline, 60, and 120 minutes post-ingestion. Questionnaires on sleep, physical activity, and dietary habits are also completed. Total time is approximately 2.5 to 3 hours. All procedures follow relevant professional guidelines.

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Countries

Japan

Contacts

Public ContactRyota Kobayashi

Teikyo University of Science Center for Arts and Sciences

rkobayashi@ntu.ac.jp03-6910-1010

Outcome results