Glucose metabolism disorder, Diabetes
Conditions
Interventions
50 mg of oligosaccharide granules (placebo) enclosed in a capsule are reacted directly with saliva in their oral cavity, and 150 g of cooked rice is immediately ingested. Subsequently, blood glucose,
Sponsors
Japan Women's University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Participants will be enrolled in the Japan Women's University during the study period and will fulfill both criteria 1) and 2). 1) Those who fulfill all the following conditions. 1. Women aged 20-29 years old 2. BMI less than 30kg/m^2 3. No impaired glucose tolerance in the past year 4. No special eating habits (unbalanced vegetarianism, etc.) or excessive exercise habits 5. No smoking habits or excessive drinking habits 6. No chronic constipation and diarrhea 7. No history of obstructive intestinal disease 8. Able to consume cooked rice 9. Able to self-measure blood glucose and undergo saliva sampling 10. Not taking medications for Sjogren's syndrome or that affect salivation * 11. No problem with being asked about their blood type 2) Those who can understand the contents of this study after receiving an explanation of the study and have given their consent to participate in the study.
Exclusion criteria
Exclusion criteria: Those who do not fulfill the inclusion criteria 1)1-11 or 2) will be excluded. Additionally, those who are inappropriate by the study director and researchers will also be excluded (such as those with moderate to severe underlying diseases).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analyze the effect of alpha-amylase inhibitor (acarbose) on salivary amylase activity and glucose metabolism 2hr after starch loading. | — |
Countries
Japan
Contacts
Public ContactAiri Sekine
Japan Women's University Dept. of Nutritional Science, Faculty of Food and Nutritional Sciences
Outcome results
None listed