Usefulness of Ultrasound Elastography for Predicting Colonic Fibrosis in Ulcerative Colitis (FIBROUS study)

A Prospective Observational Study to Evaluate the Usefulness of Ultrasound Elastography for Non-invasive Assessment of Colonic Fibrosis and Prognosis Prediction in Ulcerative Colitis - FIBROUS study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057610

Enrollment

Registered

2025-04-15

Start date

2025-03-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Diagnosed with ulcerative colitis and aged 15 years or older Scheduled to undergo colorectal resection including sigmoid colon or rectum by March 31, 2027 Able to undergo preoperative ultrasound elastography

Exclusion criteria

Exclusion criteria: Patients who have undergone total colectomy Pregnant or possibly pregnant patients Patients deemed inappropriate by the investigator

Design outcomes

Primary

Measure	Time frame
Correlation between histological degree of fibrosis in surgical specimens and elastography values	—

Secondary

Measure	Time frame
Correlation between histological inflammation and ultrasound parameters such as bowel wall thickness and color Doppler signal Association between elastography values and urgency or defecation frequency Evaluation of intra-observer agreement in elastography measurements Evaluation of clinical remission, endoscopic healing, histological improvement, and disease clearance	—

Countries

Japan

Contacts

Public ContactShintaro Sagami

Kitasato University Kitasato Institute Hospital Center for Advanced IBD Research and Treatment

jaken1013@gmail.com08053209958

Outcome results