Investigation of Acquired von Willebrand Syndrome caused by Mechanical Circulatory Support Devices

Investigation of Acquired von Willebrand Syndrome caused by Mechanical Circulatory Support Devices - Investigation of Acquired von Willebrand Syndrome caused by Mechanical Circulatory Support Devices

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057604

Enrollment

Registered

2025-05-01

Start date

2025-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult volunteers

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age 18 years or older Body weight more than 45 kg for males and more than 40 kg for females Able to provide written informed consent voluntarily

Exclusion criteria

Exclusion criteria: Individuals with chronic conditions requiring regular outpatient visits Individuals taking prescribed medications on a regular basis Individuals with a known hematologic disorder Individuals who have ever been noted to have anemia, either during a hospital visit or health screening Individuals who have participated in this study within the past four weeks Individuals who are pregnant or may be pregnant Individuals deemed unsuitable for participation as healthy volunteers by the principal investigator

Design outcomes

Primary

Measure	Time frame
von Willebrand factor antigen level, ristocetin cofactor activity (RCo), large multimer index (LMI), and platelet aggregation function assessed by total thrombus-formation analysis system (t-TAS)	—

Countries

Japan

Contacts

Public ContactMariko Hayamizu

Hokkaido University Hospital Department of Emergency Medicine

hayamizuma@gmail.com011-706-7377

Outcome results