Disinfection test of the eyelid and ocular surface using ozone nano bubble water

Disinfection test of the eyelid and ocular surface using ozone nano bubble water - Disinfection test of the eyelid and ocular surface using ozone nano bubble water

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000057603

Enrollment

Registered

2025-04-20

Start date

2025-04-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy person

Interventions

Experimental group (right eye) The skin around the eyelid is disinfected with ozone nanobubble water. After 2 minutes, oxybutocaine hydrochloride is instilled to anesthetize the surface of the eye, a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: From April 1, 2024 to March 31, 2029, healthy individuals who have obtained informed consent at Kikuna Yuda Eye Clinic, Nihon University School of Medicine Itabashi Hospital, or Yokohama Minami Kyosai Hospital.

Exclusion criteria

Exclusion criteria: Those with eye diseases, those with dry eyes, pregnant women, women who are breastfeeding, those with iodine allergies, those with drug allergies

Design outcomes

Primary

Measure	Time frame
Bacterial detection rate in scraping cultures of the skin around the eyelids and the surface of the eye	—

Secondary

Measure	Time frame
Extent of corneal epithelial damage Presence or absence of corneal irritation	—

Countries

Japan

Contacts

Public ContactYuto Yukari

Nihon University School of Medicine Itabashi Hospital Ophthalmology Ophthalmology

yukari.yuto@nihon-u.ac.jp03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026