Development and Validation of a Predictive Model for Umbilical Cord NT-proBNP Using Fetal Ultrasound

Development and Validation of a Predictive Model for Umbilical Cord NT-proBNP Using Fetal Ultrasound - Development and Validation of a Predictive Model for Umbilical Cord NT-proBNP Using Fetal Ultrasound

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057586

Enrollment

100

Registered

2025-05-26

Start date

2025-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnant women considered to be at risk of fetal cardiac overload or neonatal circulatory failure

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Participants must meet all of the following criteria: 1.Singleton pregnancy 2.Presence of at least one of the following conditions: ??. Fetal growth restriction (FGR) ??. Hypertensive disorders of pregnancy (including chronic hypertension) ??. Velamentous cord insertion ??. Abnormal cord insertion (e.g., marginal insertion, membranous insertion, tent-shaped, fork-shaped insertion) e. Fetal congenital heart disease f. Fetal arrhythmia g. Other conditions judged by the attending physician to be associated with an increased risk of fetal cardiac overload 3.Delivery at or after 22 weeks of gestation 4.Written informed consent obtained from the participant

Exclusion criteria

Exclusion criteria: Participants will be excluded if they meet any of the following criteria: 1.Unknown or unreliable gestational age 2.Any case judged by the principal investigator to be inappropriate for inclusion

Design outcomes

Primary

Measure	Time frame
Umbilical cord NT-proBNP concentration	—

Countries

Japan

Contacts

Public ContactSHOKO SAITO

Tohoku University Hospital Obstetrics and Gynecology

shoko_saito.y8k8@tohoku.ac.jp022-717-7251

Outcome results