Evaluation of Whether Coronary Artery Disease Should Be Treated First in Patients with Severe Aortic Stenosis and Concomitant Coronary Artery Disease

The Management of Coronary Artery Disease in Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation: A Single-Center Retrospective Study - Management of CAD in Patients with Severe AS Undergoing TAVI

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057561

Enrollment

220

Registered

2025-04-10

Start date

2025-02-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Stenosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with severe aortic stenosis and coronary artery disease who underwent transcatheter aortic valve implantation from October 2013 to July 2023

Exclusion criteria

Exclusion criteria: Patients with acute coronary syndrome, a prior history of coronary artery bypass grafting, or those who have undergone transcatheter aortic valve implantation using the valve-in-valve technique

Design outcomes

Primary

Measure	Time frame
A major adverse cardiac event (MACE), defined as all-cause death, myocardial infarction (MI), or unplanned revascularization (PCI or CABG)	—

Secondary

Measure	Time frame
1) All-cause death 2) Myocardial infarction 3) Unplanned revascularization (percutaneous coronary intervention or coronary artery bypass grafting) 4) Bleeding event 5) Stroke 6) Heart failure re-hospitalization 7) Procedural-related clinical complication	—

Countries

Japan

Contacts

Public ContactFutoshi Yamanaka

Shonan Kamakura General Hospital Department of Cardiology

futoshi.yamanaka@gmail.com0467461717

Outcome results