Patients with dementia-related disorders such as Alzheimer'
Conditions
Interventions
Amyloid and tau PET examinations will be conducted.
Sponsors
National Institutes for Quantum Science
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Those who meet the diagnostic criteria for Mild Cognitive Impairment (MCI) and dementia/neurodegenerative diseases (Alzheimer's Disease (AD), Corticobasal Syndrome (CBS), Progressive Supranuclear Palsy (PSP), Frontotemporal Lobar Degeneration (FTLD), Parkinson's Disease (PD) and Dementia with Lewy Bodies (DLB), Amyotrophic Lateral Sclerosis (ALS), Multiple System Atrophy (MSA)).
Exclusion criteria
Exclusion criteria: Those with organic brain disorders (head injuries requiring hospitalization or consciousness disorder, evident cerebral infarction/cerebral hemorrhage, etc.). Those with substance-related disorders (such as drug dependence). Those with complications of serious diseases, or those who have a history of such and are deemed inappropriate for this research by the physician who is a researcher. Those with magnetic metals in their body (tattoos or permanent makeup, pacemakers, etc.). Those with severe claustrophobia. Those who are pregnant, may be pregnant, or are breastfeeding. Others deemed inappropriate as research subjects by the physician who is a researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of body fluid biomarker measurements between dementia-related disorder patients and healthy controls Association between body fluid biomarkers and PET ligand accumulation distribution/brain structural changes | — |
Countries
Japan
Contacts
Public ContactKenji Tagai
National Institutes for Quantum Science and Technology National Institute for Quantum Medical Scienc Brain Functional Imaging Research Center
Outcome results
None listed