A study investigating the efficacy of a modified treat-and-extend regimen with intravitreal faricimab injections for macular edema secondary to branch retinal vein occlusion.

A study investigating the efficacy of a modified treat-and-extend regimen with intravitreal faricimab injections for macular edema secondary to branch retinal vein occlusion. - A study investigating the efficacy of a mTAE with IVF for ME secondary to BRVO.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057397

Enrollment

Registered

2025-03-25

Start date

2025-03-25

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

macular edema secondary to branch retinal vein occlusion

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Untreated macular edema secondary to branch retinal vein occlusion within one year of onset (central retinal thickness 320 micro meter or more) Willing to receive treatment Agreement to this study

Exclusion criteria

Exclusion criteria: History of anti-VEGF drug vitreous injection or steroid tenon subcapsular injection/vitreous injection History of internal ocular surgery within 3 months Presence of other diseases causing vision loss Previous vitrectomy Previous lattice photocoagulation Fellow eye is already included in the study (if both eyes are involved, the one with the larger area of occlusion will be included) Previous cerebrovascular event within 3 months Physician's judgment that the patient is not suitable for this study

Design outcomes

Primary

Measure	Time frame
Best corrected visual acuity and central area retinal thickness at 1 and 2 years after the start of treatment	—

Secondary

Measure	Time frame
The number of drug administrations, the number of outpatient visits, and the proportion of patients who were able to discontinue medication over 2 years, as well as the number of microaneurysms observed in fluorescein fundus angiography at 3 months, 1 year, and 2 years.	—

Countries

Japan

Contacts

Public ContactHidenori Takahashi

Jichi Medical University Department of Ophthalmolo

takahah-tky@umin.ac.jp0285-58-7382

Outcome results