Healthy adult
Conditions
Interventions
Mouth-rinsing using research-food-component-non-containing-mouthrinse.
Mouth-rinsing using research-food-component-cointaining-mouthrinse.
Mouth-rinsing using research-food-component-cointaining-mouth
Sponsors
Ina Food Industry Co., Ltd.
Fujita Health University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Individuals aged 18 to under 70. (2) Individuals who do not have any oral, dental, or gum diseases (not diagnosed with periodontitis or periodontal disease) and are concerned about their oral condition but do not require immediate treatment. (3) Individuals who fully understand the purpose and content of the study and voluntarily consent to participate in the research.
Exclusion criteria
Exclusion criteria: (1) Individuals diagnosed with oral diseases including periodontitis and other periodontal diseases, and those who are scheduled for dental treatment on the day of implementation. (2) Individuals who regularly consume (three or more times a week) products containing oligosaccharides such as agarooligosaccharides, or have done so within the three months prior to the pre-test. (3) Individuals diagnosed with malignancies, or those undergoing treatment for neurological disorders, heart disease, kidney disease, diabetes, thyroid dysfunction, or those with a history of severe liver diseases. However, diseases deemed by the principal investigator to have no impact on this study's evaluation, such as treatment for hypertension, are excluded. (4) Individuals who consume large amounts of alcohol (equivalent to 60 g of alcohol per day: approximately 1500 mL of beer, 540 mL of wine, 3 go [about 540 mL] of sake, or 180 mL of whiskey). (5) Individuals who are at risk of developing allergies related to the study products. (6) Individuals judged to be unsuitable as subjects based on responses to the lifestyle questionnaire. (7) Individuals who participated in another clinical study within one month prior to obtaining consent for this study, or those planning to participate in another clinical study after obtaining consent. (8) Other individuals deemed unsuitable as subjects by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in microbiota composition and diversity in the oral cavity between research-food-component-containing-mouthrinse intervention and placebo | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in questionnaires responses between research-component-containing-mouthrinse intervention and placebo | — |
Countries
Japan
Contacts
Public ContactKoji Karasawa
Ina Food Industry Co., Ltd. Research and Development Department, Development Division
Outcome results
None listed