The modulation of endogenous pain inhibitory mechanism by light irradiation

The modulation of endogenous pain inhibitory mechanism by light irradiation - The modulation of endogenous pain inhibitory mechanism by light irradiation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057375

Enrollment

Registered

2025-03-24

Start date

2025-03-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunteers

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: after informed consent is obtained, over 18 years old

Exclusion criteria

Exclusion criteria: the inability to give informed consent, under 18 years old

Design outcomes

Primary

Measure	Time frame
The evaluation of CPM effect before and after light irradiation. CPM effect is evaluated by pressure pain threshold (PPT) before and during conditioning stimulus.	—

Secondary

Measure	Time frame
the modulation of QST (the Thermal Pain Illusion(TPI), Temporal Summation(TS), Offset Analgesia(OA) etc) and the effect of background (for example, psychology test including SDS, STAI, PCS etc), and the stress evaluated by catecholamine concentrations in plasma, urine and sweat.	—

Countries

Japan

Contacts

Public ContactYuka Oono

Department of Diagnostic and Therapeutic Sciences, School of Dentistry, Meikai University Division of Dental Anesthesiology

yoono@dent.meikai.ac.jp049-279-2738

Outcome results