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Evaluation of the Effectiveness of Bronchoscopic Lung Volume Reduction (BLVR) in Severe COPD: A Prospective Exploratory Study

Evaluation of the Effectiveness of Bronchoscopic Lung Volume Reduction (BLVR) in Severe COPD: A Prospective Exploratory Study - Evaluation of the Effectiveness of Bronchoscopic Lung Volume Reduction (BLVR) in Severe COPD: A Prospective Exploratory Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000057369
Enrollment
20
Registered
2025-03-24
Start date
2025-03-13
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive lung disease

Interventions

None listed

Sponsors

Matsusaka Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with COPD scheduled for BLVR at our institution who meet the following criteria: All treatment options outlined in the latest COPD diagnosis and treatment guidelines have been considered, and all feasible non-surgical treatments have been implemented (e.g., smoking cessation, inhalation therapy, pulmonary rehabilitation, etc.). Sufficient respiratory function and overall condition to tolerate the invasiveness of the endoscopic procedure. No blood coagulation disorders. No allergies to the raw materials of the device.

Exclusion criteria

Exclusion criteria: Patients with musculoskeletal or neurological disorders that may affect physical activity levels. Patients with progressive cancer. Patients who meet contraindications for the 6-minute walk test.

Design outcomes

Primary

MeasureTime frame
Improvement in physical activity levels Improvement in pulmonary function test results Improvement in anxiety and depression Improvement in frailty and sarcopenia Improvement in body composition Evaluation of complications and incidence rate Improvement in exercise tolerance and physical function Improvement in subjective symptoms Improvement in imaging assessment parameters

Countries

Japan

Contacts

Public ContactHiroyuki Takemura

Matsusaka Municipal Hospital Department of Rehabilitation

pthiroyuki1988@gmail.com0598231515

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026