Variability of driving pressure with tidal volume delivered by predicted vs ideal body weight in class 1 obesity patient: a pilot randomized clinical trial

Variability of driving pressure with tidal volume delivered by predicted vs ideal body weight in class 1 obesity patient: a pilot randomized clinical trial - DP-PIO

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000057320

Enrollment

Registered

2025-03-25

Start date

2024-08-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity class 1 undergoing head and neck surgery

Interventions

Tidal volume calculated using predicted body weight (PBW) Patients in this group will receive mechanical ventilation with tidal volume calculated based on predicted body weight (PBW) according to t

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.- Adult patients (>18 years old) of both sexes. 2.- Rightful beneficiaries (derechohabientes) of the Instituto Mexicano del Seguro Social (IMSS). 3.- Body mass index (BMI) >30 kg/m2 <35kg/m2 (Class 1 obesity). 4.- Scheduled for elective head and neck surgery. 5.- Indicated for general anesthesia and mechanical ventilation during surgery.

Exclusion criteria

Exclusion criteria: 1.- Patients with a body mass index (BMI) lower than 30 or higher than 35. 2.- Patients with a history of obstructive pulmonary disease: asthma or chronic obstructive pulmonary disease (COPD). 3.- Patients requiring intensive care therapy in the postoperative period.

Design outcomes

Primary

Measure	Time frame
To determine whether there is a difference in driving pressure between tidal volume groups calculated based on predicted body weight vs ideal body weight, measured every 10 minutes during the first hour of head and neck surgery in class 1 obese patients.	—

Secondary

Measure	Time frame
1.- Comparison of peak pressure between tidal volumes calculated using ideal vs predicted body weight in class 1 obese patients undergoing head and neck surgery 2.- Comparison of plateau pressure between tidal volumes calculated using ideal vs predicted body weight in class 1 obese patients undergoing head and neck surgery 3.- Comparison of static compliance between tidal volumes calculated using ideal vs predicted body weight in class 1 obese patients undergoing head and neck surgery 4- Comparison of mechanical power between tidal volumes calculated using ideal vs predicted body weight in class 1 obese patients undergoing head and neck surgery.	—

Measure

Time frame

1.- Comparison of peak pressure between tidal volumes calculated using ideal vs predicted body weight in class 1 obese patients undergoing head and neck surgery 2.- Comparison of plateau pressure between tidal volumes calculated using ideal vs predicted body weight in class 1 obese patients undergoing head and neck surgery 3.- Comparison of static compliance between tidal volumes calculated using ideal vs predicted body weight in class 1 obese patients undergoing head and neck surgery 4- Comparison of mechanical power between tidal volumes calculated using ideal vs predicted body weight in class 1 obese patients undergoing head and neck surgery.

—

Countries

North America

Contacts

Public ContactYesenia Acosta

Instituto Mexicano del Seguro Social Anesthesiology

taniayesen23@gmail.com+525561676671

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026