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A prospective comparative study on the efficacy of endometrial shaving using a tissue removal system versus conventional antibiotic treatment in infertile patients with chronic endometritis

A prospective comparative study on the efficacy of endometrial shaving using a tissue removal system versus conventional antibiotic treatment in infertile patients with chronic endometritis - A prospective comparative study on the efficacy of endometrial shaving using a tissue removal system versus conventional antibiotic treatment in infertile patients with chronic endometritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000057283
Enrollment
250
Registered
2025-03-18
Start date
2025-03-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility patients with chronic endometritis

Interventions

A group that will undergo endometrial curettage using a tissue removal system. A group that will receive conventional antibiotic treatment (two weeks administration of Vibramycin)

Sponsors

Reproduction Clinic Osaka
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients who visited the hospital for assisted reproductive technology, had a positive chronic endometritis test, met the following eligibility criteria, and did not violate any of the exclusion criteria will be included in the study. -Those who provided written informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: -Those who have not given consent -Those who are deemed inappropriate by the principal investigator or co-investigator

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy rate per embryo transfer cycle

Secondary

MeasureTime frame
CD138 positive cell count before and after chronic endometritis treatment. Time to cure of chronic endometritis.

Countries

Japan

Contacts

Public ContactSatoru Sumori

Reproduction Clinic Osaka General Affairs Department

ssumori@reposaka.jp06-6136-3344

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026