Elucidation of the association of intestinal bacteria and metabolites with exacerbations of chronic obstructive pulmonary disease or pneumonia associated with COPD.

Elucidation of the association of intestinal bacteria and metabolites with exacerbations of chronic obstructive pulmonary disease or pneumonia associated with COPD. - KCER

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057281

Enrollment

100

Registered

2025-03-13

Start date

2025-02-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD exacerbation or pneumonia in COPD patients

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (i) COPD patients who meet the clinical diagnosis of COPD exacerbation or pneumonia. (ii) Patients who are 20 years of age or older. (iii) Those who have given written consent to participate in this study.

Exclusion criteria

Exclusion criteria: (i) Persons with a history of intestinal tract surgery. (ii) Persons who are deemed inappropriate to conduct this study by the Principal Investigator or Research Supervisor.

Design outcomes

Primary

Measure	Time frame
The primary endpoints of this study will be a comprehensive analysis of the bacterial flora in stools and evaluation of blood and stool metabolites.	—

Secondary

Measure	Time frame
Secondary endpoints of this study will include assessment of systemic inflammation and in vivo characterization of the intestinal microbiota in the stool.	—

Countries

Japan

Contacts

Public ContactShotaro Chubachi

Keio University Hospital Division of Pulmonary Medicine

bachibachi472000@keio.jp03-5363-3793

Outcome results