Healthy adult female
Conditions
Interventions
The test product, which is dispensed with two pushes, was applied topically twice a day for 8 weeks.
non-appplication area
Sponsors
Otsuka Pharmaceutical Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: - Healthy adult females between the ages of 50 and 80 years old. - Subjects will be divided into three age groups (50-59, 60-69, and 70-79 years old), and the first 30 subjects in each group will be selected. - Subjects with a larger average stratum corneum area measured from both the left and right hands, and with a difference of less than 15% between the two values, will be selected.
Exclusion criteria
Exclusion criteria: - Subjects with excessive sunburn on the test area at the time of consent. - Subjects with wounds, warts, or skin conditions (such as urticaria, inflammation, eczema, trauma, acne, or pimples) on the test area at the time of consent. - Subjects receiving treatment or preventive measures (such as hormone replacement therapy, pharmacotherapy, exercise therapy, dietary therapy, etc.) at medical institutions at the time of consent. - Subjects who have been exposed to ultraviolet rays beyond daily life, such as long hours of outdoor work, exercise, swimming, or leisure activities, from one month before the time of consent. - Subjects who have habitually applied or adhered makeup products, cosmetics, or quasi-drugs to the test area from one month before the time of consent. - Subjects who have shaved, depilated, or removed hair from the test area from one month before the time of consent. - Subjects who have received special skincare treatments (such as beauty salons or esthetic treatments) on the test area from one month before the time of consent. - Subjects who have habitually washed the test area with hard materials like nylon products from one month before the time of consent. - Subjects who have participated in other human trials (using cosmetics, foods, pharmaceuticals, quasi-drugs, medical devices, etc.) from one month before the time of consent. - Subjects who have habitually applied or adhered medical pharmaceuticals to the test area from six months before the time of consent. - Subjects who have previously received cosmetic medical treatments (such as Botox injections, hyaluronic acid or collagen injections, photofacials, etc.) on the test area. - Subjects with a history of hypersensitivity to cosmetics or other products, or those who may exhibit allergic symptoms. - Subjects with a history or current condition of atopic dermatitis, or those judged by the principal investigator to have symptoms resembling atopic dermatitis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surface of the stratum corneum | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin hydration, Skin observation by doctor | — |
Countries
Japan
Contacts
Public ContactSyota Shimizu
Otsuka Pharmaceutical Co., Ltd. Otsu Skin Care Research Institute
Outcome results
None listed