Small intestinal bacterial overgrowth (SIBO)
Conditions
Interventions
None listed
Sponsors
Tokai University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients suspected of having SIBO (1) Patients with abdominal symptoms such as abdominal distention and abdominal pain. (2) Patients with abnormal gas in the small intestine on plain abdominal X-ray or CT scan performed for medical reasons. (3) No evidence of organic disease (tumor, acute ulcerative lesion, severe stenosis or obstruction, etc.) on abdominal ultrasonography or upper gastrointestinal endoscopy performed for medical necessity. (4) No antimicrobial agents have been administered for 3 months prior to obtaining consent to participate in this study. (5) Age between 18 and 90 years old. (6) Consent for participation in this study is obtained from the patient by signing a consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of surgical operation for gastrointestinal diseases except for cholecystectomy, appendectomy, and hemorrhoidectomy. (2) Patients who have taken intestinal antiflatulents or intestinal peristaltic drugs within 1 month. (3) Those who have taken antibiotics within 3 months. (4) Diabetic patients with poor glycemic control (HbA1c >= 7.0%). (5) Patients taking alpha-glucosidase inhibitors. (6) Pregnant or possibly pregnant. (7) Patients with organic diseases (tumor, acute ulcerative lesion, severe stenosis or obstruction, etc.). (8) Other patients who are deemed inappropriate by the principal investigator and the study administrator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive diagnostic rate of breath test as the gold standard for SIBO diagnosis by bacterial count. Sensitivity, specificity, positive predictive value, and negative predictive value of breath test. | — |
Countries
Japan
Contacts
Public ContactTakayoshi Suzuki
Tokai University Hachioji Hospital Department of gastroenterology
Outcome results
None listed