Healthy middle-aged and older Japanese subjects
Conditions
Interventions
Duration: 24 weeks Test food: Nucleotide containing capsule Administration: Take one capsule per day * Daily dose should be taken within the day. If you forget to take the test food, take it as
Sponsors
Tashikani Plus Co., Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subjects with an MMSE score of 24 to 27 at screening and a Cognitrax standardized score of 60 to 90 for composite memory 2) Age: 50 years or older 3) Gender: Any 4) Non-smokers 5) Subjects who do not regularly consume foods designated for specified health uses, foods with functional claims, or other foods/drinks that may have functional properties 6) Subjects who do not consume foods or supplements that may affect cognitive function, such as DHA/EPA, ginkgo leaf extract, tocotrienol, astaxanthin, GABA, phosphatidylserine, plasmalogen, etc. 7) Subjects who do not consume blue fish such as sardines, mackerel, or pacific saury for more than 4 days a week 8) Subjects who do not use tools, equipment, apps, etc. that may affect cognitive function (e.g. brain training puzzles, brain training games, etc.) 9) Subjects who do not regularly use medicines (including herbal medicines) 10) Subjects who do not suffer from lifestyle-related diseases (diabetes, etc.), rheumatism, liver disorders, kidney disorders, or other chronic diseases. 11) Subjects who do not suffer from dementia. 12) Subjects who do not have irregular sleep hours or sleep habits due to night shifts, etc. 13) Subjects who do not have a history of mental illness such as depression or attention deficit hyperactivity disorder (ADHD). 14) Subjects who are currently undergoing treatment for or have a history of malignant tumors, heart failure, or myocardial infarction. 15) Subjects who do not have a pacemaker or implanted cardioverter defibrillator. 16) Subjects who have no history of allergies to medicines. 17) Subjects who are not visiting a hospital or taking medication for the purpose of treatment. 18) Subjects who fully understand the contents of the clinical trial and have given written consent.
Exclusion criteria
Exclusion criteria: 1) Pregnant or breastfeeding women or those who intend to become pregnant during the study period 2) Subjects who are participating in other clinical trials or studies, or those who have participated in other clinical trials or studies within the past 3 months 3) Subjects who are unable to follow the instructions of the doctor in charge or the medical institution staff 4) Subjects who are judged by the study administrator to have some kind of problem
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitrax | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Quality of life(POMS2, OSA-MA) 2.Safety assessment (blood tests, adverse events) | — |
Countries
Japan
Contacts
Public ContactTaisuke Fukaya
Tashikani Plus Co., Ltd CEO
Outcome results
None listed