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Effect and Mechanism of Different Training Intensities on Metabolic Control in Individuals with Diverse Metabolic Abnormalities

Effect and Mechanism of Different Training Intensities on Metabolic Control in Individuals with Diverse Metabolic Abnormalities - EMDTI-Metab

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000057053
Enrollment
300
Registered
2025-02-17
Start date
2025-01-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open public recruiting

Interventions

High-intensity interval training will be done three times a week on a cycle ergometer under supervision at the research facility for 12 weeks. Each high-intensity interval training exercise session co

Sponsors

Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Those who meet the diagnostic criteria for metabolic abnormality, including one of hypertension, diabetes, hyperlipidemia, obesity, and hyperuricemia. Sedentary behavior, at least 3 days per week, 30 minutes per day, with moderate-intensity physical activity for 3 months. Subjects are willing to participate and can sign an informed consent form.

Exclusion criteria

Exclusion criteria: Patients who are unable to cooperate in completing exercise intervention, such as those with motor dysfunction caused by neurological diseases, musculoskeletal system diseases, severe organ diseases, and other exercise contraindications; Patients with weight and glucose abnormality caused by any major chronic diseases, such as chronic kidney disease, systemic lupus erythematosus, chronic hepatitis, hypothyroidism and so on; Patients with unstable conditions, such as those with resting systolic blood pressure more than 200 mmHg or diastolic blood pressure more than 110 mmHg or recent frequent hypoglycemic events (not more than 4 mmol/L); Participants who decline participation in the program management or who have not signed the informed consent; Participants who are currently participating in other trials that may affect the results of this study.

Design outcomes

Primary

MeasureTime frame
The primary outcome measures of this study include waist circumference, blood pressure, blood sugar, triglyceride, high-density lipoprotein cholesterol.

Secondary

MeasureTime frame
Blood indicators, Timed Up and Go Test (TUGT), Short Physical Performance Battery (SPPB), muscle mass, muscle strength, 4-meter walking speed, 6-minute walk distance, dietary nutrition and sleep status, physical activity levels, and changes in maximal oxygen uptake.

Countries

Asia(except Japan)

Contacts

Public ContactPingping Cai

Shanghai University of Medicine and Health Sciences China

caipping9@163.com18759983881

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026