A cross-sectional study of the intestinal environment and frailty in older adults

A cross-sectional study of the intestinal environment and frailty in older adults - A cross-sectional study of the intestinal environment and frailty in older adults

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000057030

Enrollment

240

Registered

2025-12-31

Start date

2025-02-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy older adults

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Subjects aged 65 years or older at the time of obtaining consent 2. Subjects who have been fully informed about the study and understand its contents, and who can sign a written informed consent

Exclusion criteria

Exclusion criteria: 1. Subjects who are restricted from exercising by their physician or who cannot obtain consent from their physician to participate in this study 2. Subjects who have a history of major gastrointestinal surgery, such as gastrectomy, gastroenterostomy, or intestinal resection 3. Subjects who have participated in other clinical trials (except observational studies) within one month before obtaining consent to participate in this study 4. Subjects who are deemed inappropriate by the research director or physician to participate in this study

Design outcomes

Primary

Measure	Time frame
Gut microbiota and parameters of intestinal barrier function	—

Secondary

Measure	Time frame
Frailty score, body composition, physical function, geriatric depression scale, cognitive function, inflammation, and oxidative stress	—

Countries

Japan

Contacts

Public ContactShuichi Machida

Juntendo University Graduate School of Health and Sports Science

machidas@juntendo.ac.jp0476-98-1001

Outcome results