Colorectal liver metastasis
Conditions
Interventions
None listed
Sponsors
Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: This study includes patients with colorectal liver metastases (CLM) diagnosed as disappearing liver metastases (DLM) before surgery among those who underwent hepatic resection after preoperative chemotherapy during the study period. The study comprises a prospective cohort and a retrospective cohort. Patients scheduled for hepatic resection of CLM, including DLM, will be enrolled in the prospective cohort. Patients who had already undergone hepatic resection for CLM, including DLM, prior to the start of the study will be included in the retrospective cohort. The retrospective cohort will target cases from the past two years.
Exclusion criteria
Exclusion criteria: 1. Patients under 20 years of age at the time of consent acquisition. 2. Cases where contrast-enhanced CT or MRI was not feasible. 3. Patients deemed unfit for surgery based on their overall condition. 4. Cases with more than 50 liver metastases prior to treatment, as accurately counting them was deemed impractical. 5. Other cases deemed unsuitable as study subjects by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The recurrence rate at the site of disappeared liver metastases (DLM) in unresected cases and the pathological tumor residual rate in resected DLM cases. | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence rate, survival rate, prognostic factors, patterns of recurrence, and trends in serum tumor markers. | — |
Countries
Japan
Contacts
Public ContactKosuke Kobayashi
Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan Division of Hepatobiliary and Pancreatic Surgery
Outcome results
None listed