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Morphological evaluation after aortic valve replacement using 4D Flow MRI

Morphological evaluation after aortic valve replacement using 4D Flow MRI - Morphological evaluation after aortic valve replacement using 4D Flow MRI

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000056835
Enrollment
400
Registered
2025-01-31
Start date
2023-12-25
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic valve stenosis

Interventions

None listed

Sponsors

Sapporo Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Aortic valve stenosis

Exclusion criteria

Exclusion criteria: (1) When a patient requests to withdraw from participation in the study or withdraws consent (2) When eligibility is found to be unsatisfactory after enrollment (3) When adverse events make it difficult to continue the study (4) When there is significant noncompliance (5) When the entire study is discontinued (6) When the physician deems it appropriate to terminate the study for any other reason (6) When the physician deems it appropriate to discontinue the study for other reasons.

Design outcomes

Primary

MeasureTime frame
Primary endpoints: stroke volume, forward flow, backward flow, regurgitant fraction, ejection fraction, pressure gradient, streamlines flow from the aortic valve to the arch aorta, helical flow, vortical flow, blood velocity, energy loss, wall shear stress, and flow displacement. The primary endpoints: stroke volume, forward flow, backward flow, regurgitant fraction, ejection fraction, pressure gradient, and streamlines flow, helical flow, vortical flow, blood velocity, energy loss, wall shear stress, flow displacement, and the rate of change of these parameters with time in the aortic valve to the arch aorta.

Countries

Japan

Contacts

Public ContactTomohiro Nakajima

Sapporo Medical University Cardiovascular surgery

t.nakajima@sapmed.ac.jp011-611-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026