Elucidating bleeding-related factors in orthognathic jaw surgery under total intravenous anesthesia

Elucidating bleeding-related factors in orthognathic jaw surgery under total intravenous anesthesia - Elucidating bleeding-related factors in orthognathic jaw surgery under total intravenous anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056818

Enrollment

110

Registered

2025-01-26

Start date

2025-01-26

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

jaw deformity

Interventions

Propofol group maintains general anesthesia with propofol remimazolam group maintains general anesthesia with remimazolam

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing orthognathic surgery ASA-PS 1-2 Patient who gave consent for this study

Exclusion criteria

Exclusion criteria: <20 or >50 years of age ASA-PS 3 or higher patient who did not give consent for this study patient with a bleeding predisposition (disease, drugs) emergency surgery contraindicated for administration of medications used in this study

Design outcomes

Primary

Measure	Time frame
Correlation of endpoints to blood loss	—

Secondary

Measure	Time frame
Gender, age, weight, medical history, blood work, years of surgeon experience, type of anesthetic (propofol, remimazolam), amount of fentanyl and remifentanil used, mean systolic blood pressure, coefficient of variation of systolic blood pressure (CVSBP), mean intraoperative heart rate, duration of surgery, amount of blood loss, amount of local anesthetic used, body temperature, urine volume	—

Countries

Japan

Contacts

Public Contactmasanari nakazawa

Tokyo Dental College Dental Anesthesiology

nakazawamasanari@tdc.ac.jp03-6380-9001

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026