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Delayed Versus Immediate Coloanal Anastomosis Following Total Mesorectal Excision for Low Rectal Cancer: An International Multicenter Retrospective Cohort Study

Delayed Versus Immediate Coloanal Anastomosis Following Total Mesorectal Excision for Low Rectal Cancer: An International Multicenter Retrospective Cohort Study - DCAA vs ICAA

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000056802
Enrollment
305
Registered
2025-01-24
Start date
2024-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low Rectal Cancer

Interventions

None listed

Sponsors

Singapore General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients 18 years or older of age who underwent minimally invasive TME with hand-sewn coloanal anastomosis for primary low rectal adenocarcinoma between January 2017 and July 2023

Exclusion criteria

Exclusion criteria: Tumor-related exclusion criteria included recurrent tumors, multiple primary tumors, and non-adenocarcinomas such as neuroendocrine tumors and gastrointestinal stromal tumors. The procedure-related exclusion criteria included open surgery, emergency surgery, and multivisceral resection/pelvic exenteration. Stapled coloanal anastomosis, DCAA with a diverting stoma, and ICAA without a diverting stoma were also excluded.

Design outcomes

Primary

MeasureTime frame
the 30-day overall postoperative complication rate

Countries

Japan,Asia(except Japan)

Contacts

Public ContactIsaac Seow-En

Singapore General Hospital Department of Colorectal Surgery

isaac.seow.en@gmail.com+65-6222-3322

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026