Healthy adults
Conditions
Interventions
To apply serum twice a day to the face
To apply placebo twice a day to the face
Sponsors
Shiba Palace Clinic
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Japanese males and females aged 20 years to 59 years old??at the time of informed consent 2) Those who are not menopausal and whose menstrual cycle is stable or who have already reached menopause 3) Those who are concent to use the test product in place of the daily-used emulsion or serum 4) Those who are concent not to make any changes or additions to the skin care products currently being used during the test period, other than the teste product 5) Those who are concent not to make any changes or additions to supplementsduring the test period
Exclusion criteria
Exclusion criteria: 1) Those who have undergone or will undergo cosmetic medical treatment or special skin care procedures within 4 weeks prior to or during the test period 2) Those with history of allergic skin diseases such as atopic dermatitis 3) Those who have had allergic reactions to food or cosmetics 4) Currently undergoing treatment for a medical condition 5) Currently using drugs or supplements that have female hormone effects 6) Currently participating in another clinical test, or have participated in one within the past month 7) Those who are pregnant, lactating or possibly pregnant 8) Those who expose to ultraviolet radiation beyond daily activities such as prolonged outdoor work, exercise, swimming, leisure activities within 4 weeks prior to or during the test period 9) Those who have an irregular rhythm of life, such as those who work night shifts or day/night shifts 10) Those who smoke an average of 21 cigarettes or more per day 11) Those who engage in strenuous sports or are on a diet 12) Those who have extremely irregular eating habits 13) Those with a history of alcohol or drug dependence 14) Excessive alcohol consumption (more than 20g/day of alcohol) 6 or more days per week
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood test, skin moisture content, transepidermal water loss, ultrasound imaging of derma, skin friction coefficient, skin viscoelasticity, skin color difference, Image analysis by VISIA, questionnaire, analysis of horny cell layer at 0-4-8 weeks | — |
Countries
Japan
Contacts
Public ContactYuki Nagai
SOUKEN Co., Ltd Management Division
Outcome results
None listed