Skip to content

Multicenter Prospective Observational Study on the Efficacy of High-Flow Nasal Cannula Oxygen Therapy for Multiple Rib Fractures in Older Adults

Multicenter Prospective Observational Study on the Efficacy of High-Flow Nasal Cannula Oxygen Therapy for Multiple Rib Fractures in Older Adults - Respiratory Intervention Benefits for Rib fracturEs in older Adults Treated with High flow nasal cannula (RIBREATH) study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000056735
Enrollment
1000
Registered
2025-04-01
Start date
2025-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

multiple rib fracture

Interventions

None listed

Sponsors

Department of Acute Critical Care and Disaster Medicine, Institute of Science Tokyo
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients meeting all of the following criteria will be included in the study: 1. Individuals with three or more rib fractures requiring hospitalization. 2. Individuals aged 65 years or older at the time of enrollment. 3. Individuals requiring oxygen therapy or presenting with a respiratory rate >20 breaths per minute at the time of admission.

Exclusion criteria

Exclusion criteria: Patients meeting any of the following criteria will be excluded from the study: 1. Individuals with contraindications to HFNC (e.g., severe facial fractures that prevent HFNC placement, basilar skull fractures, untreated pneumothorax, tracheal injuries, bronchial injuries, or esophageal injuries). 2. Individuals using NIPPV at the time of admission. 3. Individuals who are intubated at the time of admission. 4. Individuals whose survival is not expected to exceed 24 hours at the time of admission. 5. Individuals who refuse to participate in this study. 6. Individuals deemed unsuitable for participation in this study by the attending physician.

Design outcomes

Primary

MeasureTime frame
The incidence rate of hospital-acquired pneumonia

Secondary

MeasureTime frame
Proportion of deaths at discharge 30-day mortality rate after admission Length of hospital stay Ventilator use rate Subjective evaluation of dyspnea Length of ICU stay Changes in the Clinical Frailty Scale Incidence rate of adverse events, including those related to HFNC

Countries

Japan

Contacts

Public ContactHoshi Hiromasa

Tsuchiura Kyodo General Hospital Department of Acute Critical Care Medicine

adg3855@gmail.com029-830-3711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026