Healthy adults
Conditions
Interventions
Consumption of the probiotic-containing test food (1 bottle per day) for 4 weeks
Consumption of the 10x probiotic-containing test food (1 bottle per day) for 4 weeks
Consumption of the placebo food (1
Sponsors
Meiji Holdings Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy men and women aged 20 to 64 years at the time of consent acquisition. The definition of a healthy subjects is as follows: -who have no history of gastrointestinal laparotomy. -who have not visited a medical institution within the past month. -who are not currently taking prescription oral or injectable medications (excluding eye drops or ointments). 2. Subjects who can give informed consent to partake in this study, after being provided with an explanation of the protocol detail.
Exclusion criteria
Exclusion criteria: 1. Subjects with a history of laparoscopic surgery of the upper digestive tract (esophagus, stomach, duodenum) or laparoscopic surgery of the lower digestive tract (small intestine, large intestine, rectum). (excluding hemorrhoids, polypectomy and endoscopic treatment). 2. Subjects who have undergone gastric X-ray barium examination, small bowel endoscopy, colonoscopy, or bowel cleansing, or taken 2 L laxatives at a clinic or at home in the month prior to the date of consent or are scheduled to do so before the date stool collection after completion of intake. 3. Subjects who plan to take prescribed oral or injectable medications (not including eye drops or ointments) the date of stool collection after completion of intake. 4. Subjects with habits of consuming milk, yogurt, lactobacillus beverages, lactobacillus or bifidobacteria supplements, or probiotics at least once a week during the month prior to the date of consent (excluding subjects who can discontinue their intake from the date of consent until stool collection after completion of intake). 5. Subjects planning to travel abroad, for more than one week, or on a business trip between the date of consent and the date of stool collection after completion of intake. 6. Subjects with allergic to milk 7. Pregnant, lactating, or possibly pregnant. 8. Subjects deemed unsuitable participation in the trial by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composition and diversity of the intestinal microbiota after 0, 2 and 4 weeks of intake | — |
Secondary
| Measure | Time frame |
|---|---|
| Stool shape Status of fatigue Sleep habits Frequency of defecation Skin condition | — |
Countries
Japan
Contacts
Public ContactSeiya Makino
Meiji Holdings Co., Ltd. Wellness Science Labs
Outcome results
None listed