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Study on 'Semi-Fowler Position MRI' for Diagnosing Cerebrospinal Fluid Leak in Minors

Study on 'Semi-Fowler Position MRI' for Diagnosing Cerebrospinal Fluid Leak in Minors - SFM study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000056727
Enrollment
10
Registered
2025-01-16
Start date
2024-12-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrospinal fluid hypovolemia

Interventions

MRI scans are generally performed in the supine position. In this study, after obtaining informed consent, we will first conduct an MRI scan in the supine position. Following this, under the same cond

Sponsors

Kochi Medical School, Kochi University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Cases presenting with orthostatic headache and suspected cerebrospinal fluid (CSF) hypovolemia. 2. Participants aged 10 years or older but under 18 years.

Exclusion criteria

Exclusion criteria: 1. Patients for whom MRI scanning is not possible.

Design outcomes

Primary

MeasureTime frame
Comparison of the dura mater in standard MRI imaging with that in imaging performed with the upper body elevated. The comparison will be conducted quantitatively if possible; however, the primary objective is to confirm the presence or absence of visible changes. The focus is on observing changes in the images caused by the change in posture.

Secondary

MeasureTime frame
1. Measurement of the anteroposterior diameter of the lumbosacral dura mater in sagittal imaging of full-spine MRI. 2. Quantification of signal intensity changes in the lumbosacral region caused by postural variation. 3. Measurement of the angle of the dura mater tip at the terminal end of the lumbosacral dura mater. 4. Evaluation of safety.

Countries

Japan

Contacts

Public ContactEiichi Nakai

Kochi Medical School, Kochi University Neurosurgery

enakai@kochi-u.ac.jp0888802397

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026