Healthy adults
Conditions
Interventions
Ingredient A-containing food (40 weeks)
Ingredient-free food (40 weeks)
Sponsors
Hokkaido Information University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Subjects who can make self-judgment and are voluntarily giving written informed consent. (2)From 60 to 75 years healthy men and women
Exclusion criteria
Exclusion criteria: (1)Subjects who are under medication for dementia, Alzheimer's disease, psychiatric disorder and cerebrovascular disease. (2)Subjects who have a history or are suspected patient of cranial nerve disease and psychiatric disorders. (3)Subjects who have serious cerebrovascular, cardiac, hepatic, renal, gastrointestinal diseases, and/or affected with infectious diseases requiring reports to the authorities. (4)Subjects who are with diabetes mellitus. (5)Subjects who have major surgical history relevant to the digestive system such as gastrectomy, gastrointestinal suture, or intestinal resection. (6)Subjects who are with systolic blood pressure of less than 90 mmHg. (7)Subjects who have unusually high and/or low blood pressure and/or abnormal hematological data. (8)Pre- or post-menopausal women complaining of obvious physical changes. (9)Subjects who have had an abnormal electrocardiogram. (10)Subjects who have had abnormal tumor marker values. (11)Subjects who have had cognitive dysfunctions. (12)Subjects with impaired renal function on the screening test (13)Subjects with impaired liver function on the screening test (14)Subjects who have difficulty swallowing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cerebral blood flow | — |
Countries
Japan
Contacts
Public ContactKentaro Nishioka
Suntory global innovation center limited. Research Institute
Outcome results
None listed