Healthy Japanese subjects
Conditions
Interventions
Test product (once a day, for 8 weeks)
Sponsors
Dermalabo Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Japanese women between the ages of 40 and 59 2. Subjects those with visual fine wrinkle grade1.00-3.00 3.Subjects non-users of anti-wrinkle cosmetics and quasi-drugs (e.g., containing retinol) in the last 3 months 4.Those who usually take care of their skin after washing their face with relatively simple care consisting of 1-3 products such as toner, milky lotion, essence, etc. 5. Subjects who can abstain from alcohol from the day before the measurement day until the end of the measurement 6. Subjects who are able to obtain written consent based on their own free will prior to the start of the study.
Exclusion criteria
Exclusion criteria: 1. Subjects those with chronic skin conditions such as atopic dermatitis, contact dermatitis, skin hypersensitivity, etc. 2. Subjects those with skin conditions that may affect the evaluation of the face as the test site 3. Subjects who experience in cosmetic medicine that affects the subject area 4. Subjects who have not received special facial care (facial equipment, esthetics, peeling, laser, etc.) for more than one month as of the date of obtaining consent 5. Subjects who have hay fever and are taking medication 6. Subjects those with allergies (drugs, food) 7. Subjects who regularly use drugs, quasi-drugs, supplements, health foods, etc. that claim to have skin beautifying effects or that may affect this study 8. Subjects whose not undergoing hormone replacement therapy for menopausal symptoms as of the date of consent, or not older than 6 months after the therapy 9. Subjects who are on a daily diet or have extremely irregular eating habits 10. Subjects with extreme sunburn or who cannot avoid prolonged outdoor work or sports 11. Subjects who excessive smoking and drinking habits and extremely irregular eating habits 12. Subjects who plan to travel abroad or go swimming in the sea between the screening and the end of the examination 13. Subjects who are lactating or pregnant, or who wish to become pregnant during the study period 14. Subjects or Subject's family is in the following occupations [cosmetics, mass media, research, clinical trial organization] 15. Subjects who have participated in a clinical trial within 4 weeks of the date consent was obtained 16. Subjects who are currently participating or will participate in another clinical trial or clinical study during the study period 17. Subjects who are judged as ineligible to participate in the study by the principal investigator and the study investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. stratum corneum water content 2. dermal water content 3. transepidermal water transpiration 4. skin viscoelasticity 5. VISIA image analysis 6. fine wrinkle image evaluation 7. VECTRA Evaluation 8. skin thickness evaluation 9. tape stripping 10. visual evaluation by a medical specialist | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. subjective questionnaire 2. logbook -- Other safety evaluation items include 1. interview and visual evaluation by a physician 2. physical examination (height, weight, BMI) *Height and BMI are performed only during SCR 3.Adverse events | — |
Countries
Japan
Contacts
Public ContactYukiyoshi Katsumata
Dermalabo Co., Ltd. Clinical Research Group
Outcome results
None listed