The Effect of Letrozole Cotreatment on Poor Responses in Ovarian Stimulation with Follitropin Delta: A Strategy for 'High AMH but Poor Response'

The Effect of Letrozole Cotreatment on Poor Responses in Ovarian Stimulation with Follitropin Delta: A Strategy for 'High AMH but Poor Response' - DeltAI study 1

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056687

Enrollment

150

Registered

2025-01-10

Start date

2021-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

2.5 mg of letrozole was orally administered daily for 5 days starting from the day follitropin delta was administered. Follitropin delta alone

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: The controlled ovarian stimulation cycles for IVF/ICSI using follitropin delta performed at Haruki Ladies Clinic in Japan from October 2021 to March 2023.

Exclusion criteria

Exclusion criteria: (1) the presence of ovarian cysts that made oocyte puncture difficult, (2) initiation of injections outside of days 2-4 of the menstrual cycle, and (3) presence of uterine fibroids (myoma uteri) that interfered with oocyte puncture.

Design outcomes

Primary

Measure	Time frame
The poor response rate of the number of oocytes retrieved	—

Secondary

Measure	Time frame
The total dosage of follitropin dela and the duration of administration	—

Countries

Japan

Contacts

Public ContactHiromasa Kuroda

Haruki Ladies Clinic The medical office

kuroda@haruki-cl.com06-6281-8801

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

The Effect of Letrozole Cotreatment on Poor Responses in Ovarian Stimulation with Follitropin Delta: A Strategy for &#39;High AMH but Poor Response&#39;