Comparison of Local Anesthetic Effects of Articaine Hydrochloride and Lidocaine Hydrochloride for mandibular wisdom tooth extraction

Comparison of Local Anesthetic Effects of Articaine Hydrochloride and Lidocaine Hydrochloride - Comparison of Local Anesthetic Effects of Articaine Hydrochloride and Lidocaine Hydrochloride

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056686

Enrollment

100

Registered

2025-01-21

Start date

2025-02-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mandibular impacted wisdom tooth

Interventions

Articaine group: 2/90,000 adrenergic 4% articaine hydrochloride (3.4~5.1mL) In 1 tube (1.7 mL), alticaine hydrochloride 68 mg, adrenergic hydrogen tartrate 0.031 mg Lidocaine group: 1/80,000 adren

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Among the patients who are scheduled to have mandibular wisdom tooth extraction under local anesthesia at the 2nd floor oral surgery outpatient department of Tsurumi University Hospital, patients aged 18 to 80 years old who have obtained consent are eligible. In addition, patients up to ASAPS2.

Exclusion criteria

Exclusion criteria: ASAPS3 or higher, psychiatric disorders (patients taking psychotropic drugs, etc.), smokers, patients with a history of hypersensitivity to amide-type local anesthetics, and patients allergic to loxoprofen sodium and amoxicillin hydrate used postoperatively

Design outcomes

Primary

Measure	Time frame
(1) Total amount of local anesthesia administered (mL) (2) VAS evaluation during tooth extraction (3) Surgery time (4) Pell-Gregory classification (5) Duration of local anesthetic (6) Start time and amount of postoperative analgesics (7) Adverse events	—

Countries

Japan

Contacts

Public ContactKeiko Abe

Tsurumi University Dental Anesthesiology

fujii-keiko@tsurumi-u.ac.jp0455808343

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026