A Single-Center Prospective Study on the Diagnostic Accuracy of Narrow-Band Imaging and Iodine Staining in Defining Lesion Extent During Endoscopic Treatment of Pharyngo-Laryngeal and Esophageal Cancer

A Single-Center Prospective Study on the Diagnostic Accuracy of Narrow-Band Imaging and Iodine Staining in Defining Lesion Extent During Endoscopic Treatment of Pharyngo-Laryngeal and Esophageal Cancer - Evaluation of the Utility of NBI Versus Iodine Staining in Determining Lesion Extent for Superficial Pharyngo-Laryngeal and Esophageal Cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000056620

Enrollment

200

Registered

2025-01-06

Start date

2020-03-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Superficial Pharyngo-Laryngeal and Esophageal Cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for endoscopic resection Esophageal squamous cell carcinoma Superficial pharyngo-laryngeal cancer Aged 20 years or older at the time of enrollment Written informed consent obtained from the patient

Exclusion criteria

Exclusion criteria: Presence of iodine allergy Inability to complete EMR/ESD or ELPS for the target lesion

Design outcomes

Primary

Measure	Time frame
Utility of NBI and Iodine Staining in Determining Lesion Extent for Pharyngo-Laryngeal and Esophageal Squamous Cell Carcinoma	—

Secondary

Measure	Time frame
Clinicopathological Characteristics of Lesions with Discrepancies in Extent Diagnosis Between Iodine Staining and NBI (Gender, Age, Medical History, Lifestyle History, Lesion Size, Lesion Depth, and Condition of the Surrounding Mucosa)	—

Countries

Japan

Contacts

Public ContactYuji Urabe

Hiroshima University Hospital Department of gastroenterology

beyan13@hiroshima-u.ac.jp082-257-5193

Outcome results