None listed
Conditions
Interventions
Sponsors
Miura Clinic, Medical Corporation Kanonkai
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Healthy males and females aged 40 to 64 years-old. 2)Subjects who are aware of skin dryness or firmness of the scalp. 3)Subjects who can make self-judgment and are voluntarily giving written informed consent.
Exclusion criteria
Exclusion criteria: Subjects(who) 1)regularly use medications affecting skin. 2)with skin disease, such as atopic dermatitis or with strange skin conditions at measurement points. 3)with severe hay fever symptoms and had been allergic symptoms. 4)have any food allergies. 5)contract or are under treatment for serious diseases (eg, liver disease, kidney disease, digestive disease, heart disease, respiratory disease, endocrine disease, vascular disorder, and/or metabolic disease). 6)had been conducted or will conduct an cosmetic operation or beauty treatment on the test spot or had been received hormone replacement therapy in the past 6 months. 7)can't avoid direct sunlight exposure, such as sunburn or sports. 8)with alopecia areata or other hair loss disorders (eczema of the head, seborrheic eczema, psoriasis, tinea capitis, or other scalp infections). 9)regularly use wigs or wigs, or who have had or are planning to have hair transplants or hair extension. 10)can't stop using supplements and/or functional foods (including Food for Specified Health Uses or Foods with Function Claims) affecting skin. 11)have a history and/or a surgical history of digestive disease affecting digestion and absorption. 12)are pregnant, breastfeed or planning to become pregnant. 13)have excessive alcohol intake more than approximately 60 g/day of pure alcohol equivalent, habit of drinking not less than 5 days a week, or can't stop drinking from the days before each measurement. 14)are under treatment for or have a history of drug addiction and/or alcoholism. 15)smoke 20 or more cigarettes a day, or cannot quit smoking during from waking to inspection completed. 16)are shiftworker and/or midnight-shift worker. 17)are planning to participate and/or had participated in other clinical studies within the last one month prior to the current study. 18)are judged as unsuitable for the current study by the investigator for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transepidermal water loss of scalp after 12 weeks of intake | — |
Secondary
| Measure | Time frame |
|---|---|
| Firmness of scalp after 12 weeks of intake, Questionnaire after 12 weeks of intake | — |
Countries
Japan
Contacts
Public ContactMakoto Terashima
Oneness Support Co., Ltd. Clinical Trial Division
Outcome results
None listed