Efficacy test of study to examine the adsorption and penetration of zinc into keratin plugs by continuous use of zinc oxide preparations

Efficacy test of study to examine the adsorption and penetration of zinc into keratin plugs by continuous use of zinc oxide preparations - Efficacy test of study to examine the adsorption and penetration of zinc into keratin plugs by continuous use of zinc oxide preparations

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056560

Enrollment

Registered

2025-01-06

Start date

2025-01-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Apply product with ZnO to the face twice a day for 1wks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Men and women aged 20-59 2. Regular employees working at Kao Corporation's Sumida Plant 3. Those who do not normally use UV preparations or makeup products that contain UV scattering agents (If you use above products, you must not use them for at least one week before participating in the study.)

Exclusion criteria

Exclusion criteria: 1.Those who are pregnant or may be pregnant, breastfeeding, or less than 6 months postpartum 2.Those who have participated in other studies (all studies using cosmetics, food, pharmaceuticals, quasi-drugs, medical devices, etc.) within the past 4 weeks, or those who have participated in other human studies during the scheduled implementation period of this study. Those who are planning to participate. 3.Those with skin symptoms such as atopic dermatitis or contact dermatitis. 4.Those with a history of allergies or rashes to cosmetics, adhesive tapes, medical tapes, etc. 5.Those with facial skin abnormalities (rash, eczema, wounds, bruises, etc.). 6.Those who have had severe sunburn on their face within the past month 7.Those who are visiting a medical institution due to poor physical condition or skin disease. 8.Those using cosmetics, quasi-drugs, or pharmaceuticals that may affect the test (peels, steroids, anti-inflammatory drugs, topical drugs, antibacterial drugs, etc.). 9.Those with seasonal allergies such as severe hay fever. 10.Those who have received cosmetic treatment for the face (laser treatment, collagen injection, etc.). 11.Those who have had aesthetic treatment on their face within the past month 12.Those who use home facial beauty devices or beauty equipment 13.Those who have a habit of smoking. 14.Those who are deemed unsuitable for research participation by the research director due to violation of compliance obligations, etc.

Design outcomes

Primary

Measure	Time frame
Evaluation of the amount of zinc adsorbed onto the surface of keratin plugs and the degree of zinc penetration into the keratin plugs after one week of continuous use of the preparation	—

Countries

Japan

Contacts

Public ContactMasafumi Takata

Kao Corporation Skin Care Research Lab.

takata.masafumi@kao.com+81-3-5630-7286

Outcome results