Whether listening to music containing the Solfeggio frequency (528Hz) during the execution of simple arithmetic tasks reduces psychological stress.

Whether listening to music containing the Solfeggio frequency (528Hz) during the execution of simple arithmetic tasks reduces psychological stress. - Whether listening to music containing the Solfeggio frequency (528Hz) during the execution of simple arithmetic tasks reduces psychological stress.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056517

Enrollment

Registered

2024-12-25

Start date

2024-08-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Interventions

Engage in simple arithmetic tasks under silent conditions. Listen to music containing 528Hz frequency (Solfeggio music) during simple arithmetic tasks. Listen to music with a standard scale during sim

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Third and fourth-year students enrolled in the Faculty of Rehabilitation at Hyogo Medical Univerity.

Exclusion criteria

Exclusion criteria: Individuals with visual impairments that may affect the performance of the Kraepelin test. Individuals with hearing impairments that may affect how music is perceived. Individuals with metabolic disorders that may affect salivary secretion (such as thyroid dysfunction, anemia, hypoglycemia, hypoalbuminemia, etc.).

Design outcomes

Primary

Measure	Time frame
salivary amylase levels	—

Secondary

Measure	Time frame
Uchida-Kraepelin Psychodiagnostic Test results Profile of Mood States 2 (POMS2) NASA Task Load Index (NASA-TLX)	—

Countries

Japan

Contacts

Public ContactTsunehiro Otsuka

Hyogo Medical University Faculty of rehabilitation

ts-ootsuka@hyo-med.ac.jp0783043185

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026