Type 2 diabetes
Conditions
Interventions
high-intensity interval training
Walking
No special physical activity (control)
Sponsors
Kobe University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients diagnosed with type 2 diabetes mellitus, not on insulin therapy, and fasting blood glucose level less than 140 mg/dL, and those who do not have an exercise habit (at least twice a week for at least 30 minutes each time).
Exclusion criteria
Exclusion criteria: a person who is unable to perform HIIT due to a musculoskeletal disorder, a person who is restricted from exercising by his/her physician, a person who has a urine ketone body positive and blood glucose level of 250 mg/dL or higher, a person with pre proliferative retinopathy or higher, a person with over manifest nephropathy (eGFR < 30 mL/min/1.73 m2 or urine albumin level > 300 mg/gCr or urinary protein level of 0.5 g/gCr or higher), ischemic heart disease or cardiopulmonary impairment, uncontrolled hypertension (180/110 mmHg or higher), dyslipidemia (LDL cholesterol level of 140 mg/dL or higher, HDL cholesterol level of less than 40 mg/dL, triglyceride level of less than 40 mg/gCr or higher), and other conditions. HDL cholesterol level less than 40 mg/dL, triglyceride level more than 150 mg/dL), and those with a family history of cardiovascular disease or smoking history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insulin resistance (HOMA-IR) | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting insulin, fasting blood glucose, heart rate, blood pressure, subjective exercise intensity | — |
Countries
Japan
Contacts
Public ContactKumiko Ono
Kobe University Graduate School of Health Sciences
Outcome results
None listed