Influence of sex differences considering menstrual cycle on late brain activity(after 100ms post-stimulation)

Influence of sex differences considering menstrual cycle on late brain activity(after 100ms post-stimulation) - Influence of sex differences considering menstrual cycle on late brain activity(after 100ms post-stimulation)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000056458

Enrollment

Registered

2024-12-31

Start date

2024-12-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy adults

Interventions

Electrical Stimulation Auditory Stimulation EEG Electrical Stimulation Auditory Stimulation EEG Electrical Stimulation Auditory Stimulation EEG

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Right-handed normal adult men and women Females are normal menstruating adults (menstrual cycle of 28 to 35 days) Adults with no history of psychiatric or neurological disorders

Exclusion criteria

Exclusion criteria: Adults with no history of psychiatric or neurological disorders Women with irregular menstruation

Design outcomes

Primary

Measure	Time frame
In order to investigate the effect of sex difference on late brain activity (after 100 ms of stimulus presentation), we record somatosensory evoked potentials (SEPs) and auditory evoked potentials (AEPs) during simple response and resting conditions using electroencephalogram (EEG) and evaluate the sex difference. In this process, women are measured in two periods: the menstrual period and the ovulatory period. The menstrual period is defined as the period from the second to the fourth day after the onset of menstruation, and the ovulatory period is defined as the period from the second to the fourth day after a positive urine ovulation test. This allows for detailed clarification of sex differences in higher-order brain function. It also provides evidence that it is important to consider the menstrual cycle (sex hormones) and sex differences when examining neurophysiological sex differences.	—

Measure

Time frame

In order to investigate the effect of sex difference on late brain activity (after 100 ms of stimulus presentation), we record somatosensory evoked potentials (SEPs) and auditory evoked potentials (AEPs) during simple response and resting conditions using electroencephalogram (EEG) and evaluate the sex difference. In this process, women are measured in two periods: the menstrual period and the ovulatory period. The menstrual period is defined as the period from the second to the fourth day after the onset of menstruation, and the ovulatory period is defined as the period from the second to the fourth day after a positive urine ovulation test. This allows for detailed clarification of sex differences in higher-order brain function. It also provides evidence that it is important to consider the menstrual cycle (sex hormones) and sex differences when examining neurophysiological sex differences.

—

Secondary

Measure	Time frame
Somatosensory evoked potentials (SEPs) and auditory evoked potentials (AEPs) during simple response and resting conditions will be recorded using electroencephalography (EEG) to evaluate differences in women's menstrual cycle periods. In this process, women will be measured in two periods: the menstrual cycle and the ovulatory cycle. The menstrual cycle is defined as the period from the second to the fourth day after the onset of menstruation, and the ovulatory cycle is defined as the period from the second to the fourth day after a positive urine ovulation test. This allows for detailed clarification of sex differences in higher-order brain function. It also provides evidence that it is important to consider the menstrual cycle (sex hormones) and sex differences when examining neurophysiological sex differences.	—

Measure

Time frame

Somatosensory evoked potentials (SEPs) and auditory evoked potentials (AEPs) during simple response and resting conditions will be recorded using electroencephalography (EEG) to evaluate differences in women's menstrual cycle periods. In this process, women will be measured in two periods: the menstrual cycle and the ovulatory cycle. The menstrual cycle is defined as the period from the second to the fourth day after the onset of menstruation, and the ovulatory cycle is defined as the period from the second to the fourth day after a positive urine ovulation test. This allows for detailed clarification of sex differences in higher-order brain function. It also provides evidence that it is important to consider the menstrual cycle (sex hormones) and sex differences when examining neurophysiological sex differences.

—

Countries

Japan

Contacts

Public ContactSayaka Anazawa

Niigata University of Health and Welfare Graduate School of Health and Welfare Studies

hwd24012@nuhw.ac.jp070-2029-1720

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026