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Quantitative assessment of sports-related concussion using blood biomarkers

Quantitative assessment of sports-related concussion using blood biomarkers - Quantitative assessment of sports-related concussion using blood biomarkers

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000056410
Enrollment
60
Registered
2025-03-01
Start date
2025-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sports-related concussion

Interventions

None listed

Sponsors

International University of Health and Welfare
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged 20 years or older who suffered a head injury during a sporting event between February 1, 2025 and January 31, 2027, were aware of symptoms of a concussion, and visited the research institution's concussion outpatient clinic within 24 hours of the injury.

Exclusion criteria

Exclusion criteria: Patients with unknown time of trauma Patients with a primary diagnosis of ischemic or hemorrhagic stroke at the enrollment site Patients unable to perform venipuncture (compromised skin integrity at the venipuncture site, vascular calcification (i.e., IV drug users, advanced atherosclerosis), missing both upper limbs (congenital or amputee)) Patients unable to enter the CT scanner (e.g., morbid obesity or claustrophobia) Patients who received a blood transfusion after head trauma and before blood collection for this study Pregnant or breastfeeding female patients Patients for whom written consent could not be obtained Severely hemolyzed or turbid blood sample Severely insufficient sample volume (1mL or less)

Design outcomes

Primary

MeasureTime frame
Relationship between concussion (diagnosed by SCAT5) and blood biomarkers values (GFAP, UCH-L1)

Secondary

MeasureTime frame
Relationship between organic abnormalities (diagnosed by MRI) and blood biomarker values (GFAP, UCH-L1) Relationship between time to return to competition and blood biomarker values (GFAP, UCH-L1)

Countries

Japan

Contacts

Public ContactEiichi Suehiro

International University of Health and Welfare Narita Hospital Neurosurgery

esuehiro@iuhw.ac.jp0476355600

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026