Atopic dermatitis, rosacea (erythematotelangiectatic rosacea), acne
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Persons who have received an explanation of this study, understand it, and agree to participate in the study of their own free will (persons who have indicated informed consent). 2. Those who have subjective symptoms of sensitive skin and have a history of various skin diseases (AD, ETR, acne), or have self-recognition of such diseases. (iii) Persons who have completed the consent form and other documents. 3. Those who are able to fill out the consent form and other documents. 4. who are able to come to the designated facility on the day of the examination.
Exclusion criteria
Exclusion criteria: 1. those with trauma scars or surgical scars on the cheek area (including under the eyes) 2. who have undergone cosmetic medical procedures (laser, photofacial, injection therapy, HIFU, etc.) or cosmetic surgical procedures (incision, thread lift, etc.) that affect the shape of the face 3. who have excessive suntanning on the face 4. who regularly visits tanning salons 5. who have been exposed to significant sun exposure before the day of this examination (e.g., sports activities during the daytime over a series of days) 6. who is expected to suffer from severe hay fever* by the day of the main examination (*level that requires a hospital visit) 7. those who drink alcohol excessively on a regular basis 8. who use corticosteroids (steroids) or immunomodulators (e.g., tacrolimus) on the face before the study date 8. is expected to use corticosteroids (steroids) or immunomodulators (e.g., tacrolimus) on the face before the study date 9. who are receiving hormone replacement therapy 10. taking oral contraceptives 11. who are allergic to rubbing alcohol or rubber 12. pregnant or lactating 13. who is currently participating in another clinical research study 14. who is currently participating in another clinical research study 14. who have symptoms of the common cold or a fever of 37.5 degrees Celsius or higher 15. who have a history of serious hepatic disorder, renal disorder, or myocardial infarction 16. those with severe anemia Persons who have experienced sickness during blood collection. 18. 18. who have keloids (scars that are red, swollen, and difficult to heal) 19. who suffer from diabetes mellitus 20. who use antithrombotic drugs 20. who are using antithrombotic drugs 21. any other person deemed inappropriate by the principal investigator involved in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene expression in skin samples | — |
Secondary
| Measure | Time frame |
|---|---|
| Age, gender, information on skin diseases, allergic predisposition (obtained by blood test), facial image, skin property measurements (obtained by spectrophotometer, MPA), stratum corneum (obtained by tape stripping), presence of sensory irritation (obtained by lactic acid sting test), menstrual cycle, history of allergy/related diseases, lifestyle habits information (obtained by questionnaire). | — |
Countries
Japan
Contacts
POLA Chemical Industries, Inc. FRONTIER RESEARCH CENTER