Skip to content

Effects of tranexamic acid on sore throat pain associated with acute upper respiratory tract infection: a randomized, controlled trial

Effects of tranexamic acid on sore throat pain associated with acute upper respiratory tract infection: a randomized, controlled trial - Effects of tranexamic acid on sore throat pain: a randomized, controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000056394
Enrollment
80
Registered
2024-12-08
Start date
2023-11-06
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

upper respiratory tract infection

Interventions

Patients receive 1g of 50% tranexamic acid preparation of with a cup of water. Patients receive 1g placebo (lactose), desolved with a cup of water.

Sponsors

Akashi Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients of upper respiratory tract infections with a complaint of sore throat, who visited a general internal medicine department office in the Akashi medical center hospital from November 2023 to October 2024 were registered.

Exclusion criteria

Exclusion criteria: Patients with allergy to tranexamic acid and lactose, pregnant patients or patients with possibility of pregnancy, breastfeeding patients, patients who take tranexamic acid, patients who were unable to participate the study because of dementia, visual impairment and unable to answer, or complete the study form.

Design outcomes

Primary

MeasureTime frame
The proportion of patients with sore throat score more than moderate level between 2 hours after tranexamic acid is taken.

Secondary

MeasureTime frame
Primary outcome is the difference on sore throat VAS scale between 10 minutes after tranexamic acid is taken.

Countries

Japan

Contacts

Public ContactNaoto Ishimaru

Akashi Medical Center Department of General Internal Medicine

maru-tkb@umin.ac.jp0789361101

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026